Article
Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
Cell - 24 Nov 2004
Clayton Gina M, Silverman William R, Heginbotham Lise, Morais-Cabral João H
Abstract excerpt
Here we describe the initial functional characterization of a cyclic nucleotide regulated ion channel from the bacterium Mesorhizobium loti and present two structures of its cyclic nucleotide binding domain, with and without cAMP. The domains are organized as dimers with the interface formed by t...
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