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Article

Mapping the rho1 GABA(C) receptor agonist binding pocket. Constructing a complete model.

The Journal of biological chemistry - 14 Jan 2005

Sedelnikova Anna, Smith Craig D, Zakharkin Stanislav O, Davis Delores, Weiss David S, Chang Yongchang

Abstract excerpt

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain. The GABA receptor type C (GABA(C)) is a ligand-gated ion channel with pharmacological properties distinct from the GABA(A) receptor. To date, only three binding domains in the recombinant rho1 GABA(C)...

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Identifiers

PMID: 15548535
DOI: 10.1074/jbc.M409908200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15548535-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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