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Article

The transcriptional and translational landscape of HCoV-OC43 infection

27 Jan 2025

Abstract excerpt

The coronavirus HCoV-OC43 circulates continuously in the human population and is a frequent cause of the common cold. Here, we generated a high-resolution atlas of the transcriptional and translational landscape of OC43 during a time course following infection of human lung fibroblasts. Using ribosome profiling, we quantified the relative expression of the canonical open reading frames (ORFs) and identified...

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PMID: 39869630
DOI: 10.1371/journal.ppat.1012831

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