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Article

Human respiratory coronavirus OC43: genetic stability and neuroinvasion.

Journal of virology - 1 Aug 2004

St-Jean Julien R, Jacomy Hélène, Desforges Marc, Vabret Astrid, Freymuth François, Talbot Pierre J

Abstract excerpt

The complete genome sequences of the human coronavirus OC43 (HCoV-OC43) laboratory strain from the American Type Culture Collection (ATCC), and a HCoV-OC43 clinical isolate, designated Paris, were obtained. Both genomes are 30,713 nucleotides long, excluding the poly(A) tail, and only differ by 6 nucleotides. These six mutations are scattered throughout the genome and give rise to only two amino acid...

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Identifiers

PMID: 15280490
DOI: 10.1128/JVI.78.16.8824-8834.2004
PMCID: PMC479063

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