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Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes

1 Dec 2006

Abstract excerpt

BACKGROUND: The genome of coronaviruses contains structural and non-structural genes, including several so-called accessory genes. All group 1b coronaviruses encode a single accessory protein between the spike and envelope genes, except for human coronavirus (HCoV) 229E. The prototype virus has a split gene, encoding the putative ORF4a and ORF4b proteins. To determine whether primary HCoV-229E isolates exhibit...

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PMID: 17194306
DOI: 10.1186/1743-422x-3-106

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