Article
TBL2 methylation is associated with hyper-low-density lipoprotein cholesterolemia: a case-control study.
Lipids in health and disease - 18 Aug 2020
Li Yang, Liu Shuai, Wang Yong-Tao, Min Han, Adi Dilare, Li Xiao-Mei, Yang Yi-Ning, Fu Zhen Yan, Ma Yi-Tong
Abstract excerpt
BACKGROUND: HMGCR, SCAP, SREBF1, SREBF2 and TBL2 are well-known genes that are involved in the process of lipid metabolism. However, it is not known whether epigenetic changes of these genes are associated with lipid metabolism. In this study, the methylation levels of the HMGCR, SCAP, SREBF1, SREBF2 and TBL2 genes were analyzed between samples from a hyper-low-density lipoprotein cholesterolemia (hyper-LDL)...
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