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Differential expression of α‐synuclein isoforms in dementia with Lewy bodies

9 Jul 2004

Abstract excerpt

Dementia with Lewy bodies (DLB) is characterized by the widespread presence of Lewy bodies (LBs) in the brain. alpha-Synuclein, the main component of LBs, is expressed as two main isoforms (112 and 140), but little is known about their differential expression in the brain. We compared alpha-synuclein 112 and alpha-synuclein 140 expression levels in the prefrontal cortices of six DLB patients, eight Alzheimer...

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PMID: 15541000
DOI: 10.1111/j.1365-2990.2004.00572.x

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