Article
Regulation of adenylate cyclase type VIII splice variants by acute and chronic Gi/o-coupled receptor activation.
The Biochemical journal - 1 Mar 2005
Steiner Debora, Avidor-Reiss Tomer, Schallmach Ester, Butovsky Elena, Lev Nirit, Vogel Zvi
Abstract excerpt
We previously reported that acute agonist activation of G(i/o)-coupled receptors inhibits adenylate cyclase (AC) type VIII activity, whereas agonist withdrawal following chronic activation of these receptors induces AC-VIII superactivation. Three splice variants of AC-VIII have been identified, w...
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