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Article

A novel peptide isolated from a phage display peptide library with trastuzumab can mimic antigen epitope of HER-2.

The Journal of biological chemistry - 11 Feb 2005

Jiang Beihai, Liu Wenbin, Qu Hong, Meng Lin, Song Shumei, Ouyang Tao, Shou Chengchao

Abstract excerpt

Trastuzumab, a humanized antibody to HER-2, has been shown to be effective in the treatment of breast cancer in which HER-2 overexpression and metastasis occurs. In our search for an effective mimic epitope of HER-2 binding with trastuzumab and to develop HER-2 peptide vaccine, we screened a phage display 12-mer peptide library with trastuzumab as the target. A mimetic peptide (mimotope) H98 (LLGPYELWELSH) that...

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PMID: 15536075
DOI: 10.1074/jbc.M411047200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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