Article
Myocardial-tissue-specific phenotype of maternal microchimerism in neonatal lupus congenital heart block.
Lancet (London, England) - 15 Nov 2003
Stevens Anne M, Hermes Heidi M, Rutledge Joe C, Buyon Jill P, Nelson J Lee
Abstract excerpt
BACKGROUND: During pregnancy, maternal cells pass into the fetus, where they can persist for many years after birth. We investigated the presence of maternal cells in neonatal lupus syndrome (NLS), an autoimmune disease that develops in utero. The most serious complication of NLS is inflammation of the atrioventricular node leading to congenital heart block (CHB). METHODS: In a blinded case-control study,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.