Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crystal structure of a human CD3-ε/δ dimer in complex with a UCHT1 single-chain antibody fragment

8 Nov 2004

Abstract excerpt

The alpha/beta T cell receptor complex transmits signals from MHC/peptide antigens through a set of constitutively associated signaling molecules, including CD3-epsilon/gamma and CD3-epsilon/delta. We report the crystal structure at 1.9-A resolution of a complex between a human CD3-epsilon/delta ectodomain heterodimer and a single-chain fragment of the UCHT1 antibody. CD3-epsilon/delta and CD3-epsilon/gamma share...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15534202
DOI: 10.1073/pnas.0407359101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crystal structure of a human CD3-ε/δ dimer in complex with a UCHT1 single-chain antibody fragmentPMID 15534202Read ↗

Crystal structure of the human T cell receptor CD3εγ heterodimer complexed to the therapeutic mAb OKT3Semantic proximity Read ↗

Structures of human γδ T cell receptor–CD3 complexSemantic proximity Read ↗

Crystal structure of the human LAG-3–HLA-DR1–peptide complexSemantic proximity Read ↗

Structure of the Vδ domain of a human γδ T-cell antigen receptorSemantic proximity Read ↗

One of the CD3ε Subunits within a T Cell Receptor Complex Lies in Close Proximity to the Cβ FG LoopSemantic proximity Read ↗

TMX1, a disulfide oxidoreductase, is necessary for T cell function through regulation of CD3ζSemantic proximity Read ↗

Structure of a fully assembled γδ T cell antigen receptorSemantic proximity Read ↗

Distinctive CD3 Heterodimeric Ectodomain Topologies Maximize Antigen-Triggered Activation of αβ T Cell ReceptorsSemantic proximity Read ↗

Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complex.Semantic proximity Read ↗

A structural basis for 14-3-3sigma functional specificity.Semantic proximity Read ↗

Crystal structure of the anti-His tag antibody 3D5 single-chain fragment complexed to its antigen.Semantic proximity Read ↗

The CD3-gamma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.