Article
Impact of HLA class I high-resolution mismatches on chronic graft-versus-host disease and survival of patients given hematopoietic stem cell grafts from unrelated donors.
Bone marrow transplantation - 1 Jan 2005
Greinix H T, Faé I, Schneider B, Rosenmayr A, Mitterschiffthaler A, Pelzmann B, Kalhs P, Lechner K, Mayr W R, Fischer G F
Abstract excerpt
There is consensus that matching of unrelated donors (URD) and patients for HLA class II alleles improves the outcome of hematopoietic stem cell transplantation (HSCT). However, the significance of HLA class I allelic mismatches for transplant outcome is under discussion and reports on long-term effects like chronic graft-versus-host disease (GVHD) are rare. Thus, we investigated the association of human...
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