Article
Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.
The Journal of clinical endocrinology and metabolism - 1 Nov 2004
Day Ian N M, Chen Xiao-He, Gaunt Tom R, King Tabitha H T, Voropanov Anca, Ye Shu, Rodriguez Santiago, Syddall Holly E, Sayer Avan Aihie, Dennison Elaine M, Tabassum Faiza, Barker David J P, Cooper Cyrus, Phillips David I W
Abstract excerpt
Low rates of fetal and infant growth are associated with the metabolic syndrome and cardiovascular disease in later life. We investigated common genetic variation in the GH-CSH gene cluster on chromosome 17q23 encoding GH, placental lactogens [chorionic somatomammotropins (CSH)], and placental GH variant in relation to fetal and infant growth and phenotypic features of the metabolic syndrome in subjects aged...
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