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Differential Expression Profile of<i>Growth Hormone/Chorionic Somatomammotropin</i>Genes in Placenta of Small- and Large-for-Gestational-Age Newborns

17 Mar 2010

Abstract excerpt

CONTEXT: The human growth hormone/chorionic somatomammotropin (hGH/CSH) locus at 17q22-24, consisting of one pituitary-expressed postnatal (GH1) and four placenta-expressed genes (GH2, CSH1, CSH2, and CSHL1), is implicated in regulation of postnatal and intrauterine growth. A positive correlation has been reported between the offspring's birth weight and serum placental GH (coded by GH2) and placental lactogen...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 20233782
DOI: 10.1210/jc.2010-0023

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