Article
Lack of association between two polymorphisms of brain-derived neurotrophic factor and response to typical neuroleptics.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jul 2005
Anttila S, Illi A, Kampman O, Mattila K M, Lehtimäki T, Leinonen E
Abstract excerpt
Several studies have connected brain-derived neurotrophic factor (BDNF) with treatment response to neuroleptics. In recent studies, the BDNF expression was reduced by typical neuroleptics. We conducted a retrospective study on 94 patients with schizophrenia and 98 controls. The BDNF G196A and C270T polymorphisms are not associated with treatment response to typical neuroleptics or with age at first...
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