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Article

Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews.

The New England journal of medicine - 4 Nov 2004

Aharon-Peretz Judith, Rosenbaum Hanna, Gershoni-Baruch Ruth

Abstract excerpt

BACKGROUND: A clinical association has been reported between type 1 Gaucher's disease, which is caused by a glucocerebrosidase deficiency owing to mutations in the glucocerebrosidase gene (GBA), and parkinsonism. We examined whether mutations in the GBA gene are relevant to idiopathic Parkinson's disease. METHODS: A clinic-based case series of 99 Ashkenazi patients with idiopathic Parkinson's disease, 74...

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PMID: 15525722
DOI: 10.1056/NEJMoa033277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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