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Article

The dopamine-4 receptor gene associated with binge eating and weight gain in women with seasonal affective disorder: an evolutionary perspective.

Biological psychiatry - 1 Nov 2004

Levitan Robert D, Masellis Mario, Basile Vincenzo S, Lam Raymond W, Kaplan Allan S, Davis Caroline, Muglia Pierandrea, Mackenzie Bronwyn, Tharmalingam Subi, Kennedy Sidney H, Macciardi Fabio, Kennedy James L

Abstract excerpt

BACKGROUND: We recently described a preliminary association between the hypofunctional seven-repeat allele of the dopamine-4 receptor gene (DRD4) and increased maximal lifetime body mass index in women with seasonal affective disorder (SAD). In this study, we examined whether binge eating behavior mediated this putative association. METHODS: The study sample consisted of 131 women with winter SAD who reported...

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Identifiers

PMID: 15522250
DOI: 10.1016/j.biopsych.2004.08.013

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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