Article
Association between the seven-repeat allele of the dopamine-4 receptor gene (DRD4) and spontaneous food intake in pre-school children.
Appetite - 1 Feb 2014
Silveira Patrícia Pelufo, Portella André Krumel, Kennedy James L, Gaudreau Hélène, Davis Caroline, Steiner Meir, Soares Claudio N, Matthews Stephen G, Sokolowski Marla B, Dubé Laurette, Loucks Eric B, Hamilton Jill, Meaney Michael J, Levitan Robert D
Abstract excerpt
BACKGROUND: Studies in adults show associations between the hypofunctional seven-repeat allele (7R) of the dopamine-4 receptor gene (DRD4), increased eating behaviour and/or obesity, particularly in females. We examined whether 7R is associated with total caloric intake and/or food choices in pre-schoolers. METHODS: 150 four-year-old children taking part in a birth cohort study in Canada were administered a snack...
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