Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A636P testing in Ashkenazi Jews.

Familial cancer - 1 Jan 2004

Guillem Jose G, Moore Harvey G, Palmer Crystal, Glogowski Emily, Finch Rob, Nafa Khedoudja, Markowitz Arnold J, Offit Kenneth, Ellis Nathan A

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited colorectal cancer syndrome attributable to mutations in one of several DNA mismatch repair genes, most commonly MLH1 and MSH2 . In certain populations, founder mutations account for a substantial portion of HNP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Age Distribution
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MutL Protein Homolog 1

Share to Neoplasm Proteins

Share to Sex Distribution

Share to Survival Analysis

Source

Identifiers

PMID: 15516845
DOI: 10.1007/s10689-004-0899-z

Genes

MSH2
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15516845-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A636P testing in Ashkenazi Jews.PMID 15516845Read ↗

The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population.Semantic proximity Read ↗

A636P is associated with early-onset colon cancer in Ashkenazi Jews.Semantic proximity Read ↗

High risk of colorectal and endometrial cancer in Ashkenazi families with the MSH2 A636P founder mutation.Semantic proximity Read ↗

Characterization of two Ashkenazi Jewish founder mutations in MSH6 gene causing Lynch syndrome.Semantic proximity Read ↗

An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.Semantic proximity Read ↗

Gynecologic malignancies in Ashkenazi families with the MSH2 A636P founder mutation.Semantic proximity Read ↗

Lynch Syndrome in high risk Ashkenazi Jews in Israel.Semantic proximity Read ↗

Hereditary cancer screening: Case reports and review of literature on ten Ashkenazi Jewish founder mutations.Semantic proximity Read ↗

The founder Ashkenazi Jewish mutations in the MSH2 and MSH6 genes in Israeli patients with gastric and pancreatic cancer.Semantic proximity Read ↗

Mutation spectrum in HNPCC in the Israeli population.Semantic proximity Read ↗

The HNPCC associated MSH2*1906G-->C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population.Semantic proximity Read ↗

Cancer Susceptibility Genetic Testing in a High-Risk Cohort of Urban Ashkenazi Jewish Individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.