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Article

Lynch Syndrome in high risk Ashkenazi Jews in Israel.

Familial cancer - 1 Mar 2014

Goldberg Yael, Kedar Inbal, Kariiv Revital, Halpern Naama, Plesser Morasha, Hubert Ayala, Kaduri Luna, Sagi Michal, Lerer Israela, Abeliovich Dvorah, Hamburger Tamar, Nissan Aviram, Goldshmidt Hanoch, Solar Irit, Geva Ravit, Strul Hana, Rosner Guy, Baris Hagit, Levi Zohar, Peretz Tamar

Abstract excerpt

Lynch Syndrome is caused by mutations in DNA mismatch repair genes. Diagnosis is not always trivial and may be costly. Information regarding incidence, genotype-phenotype correlation, spectrum of mutations and genes involved in specific populations facilitate the diagnostic process and contribute to clinical work-up. To report gene distribution, mutations detected and co-occurrence of related syndromes in a...

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Topics

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Share to Antigens, Neoplasm
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23990280
DOI: 10.1007/s10689-013-9675-2

Genes

MSH2
MSH6
MLH1

Provenance

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