Article
Gene expression and immune response kinetics using electroporation-mediated DNA delivery to muscle
27 Oct 2004
Abstract excerpt
BACKGROUND: Injection of DNA encoding exogenic proteins into muscle tissue combined with electroporation often results in a transient increase of the encoded protein concentration in the muscle and the blood. The reduction is normally due to an immune response against the exogenic protein but other factors may also be involved. How various electroporation parameters affect the concentration kinetics of syngenic...
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