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Article

Microsphere bead arrays and sequence validation of 5/7/9T genotypes for multiplex screening of cystic fibrosis polymorphisms.

The Journal of molecular diagnostics : JMD - 1 Nov 2004

Hadd Andrew G, Laosinchai-Wolf Walairat, Novak Chris R, Badgett Marty R, Isgur Lesley A, Goldrick Marianna, Walkerpeach Cindy R

Abstract excerpt

The development of simple and rapid methods for the detection of the common genetic mutations associated with cystic fibrosis (CF) requires access to positive-control samples including the 5/7/9T variants of intron 8. We used PCR and a simple multiplex bead-array assay to identify 5/7/9T control samples from 29 commercially available DNA samples. Unpurified PCR products were directly hybridized to color-coded...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15507674
DOI: 10.1016/S1525-1578(10)60531-4
PMCID: PMC1867485

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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