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Article

Multiplex allele-specific fluorescent PCR for haplotyping the IVS8 (TG)m(T)n locus in the CFTR gene.

Clinical chemistry - 1 Sept 2008

Costa Catherine, Costa Jean-Marc, Martin Josiane, Boissier Brigitte, Goossens Michel, Girodon Emmanuelle

Abstract excerpt

BACKGROUND: Precise genotyping of the intron 8 poly(TG) and poly(T) tracts of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is of clinical relevance in CFTR pathology. The (TG)(m) locus influences the penetrance of the (T)(5) allele, which may be associated with male infertility by congenital bilateral absence of the vas deferens (CBAVD) or other CFTR-related disorders (CFTR-RD), in...

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Source

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Identifiers

PMID: 18755906
DOI: 10.1373/clinchem.2008.103259
PMCID: PMC4710781

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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