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Turning on stem cell cardiogenesis with extremely low frequency magnetic fields

26 Oct 2004

Abstract excerpt

Modulation of stem cell differentiation is an important assignment for cellular engineering. Embryonic stem (ES) cells can differentiate into cardiomyocytes, but the efficiency is typically low. Here, we show that exposure of mouse ES cells to extremely low frequency magnetic fields triggered the expression of GATA-4 and Nkx-2.5, acting as cardiac lineage-promoting genes in different animal species, including...

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PMID: 15507470
DOI: 10.1096/fj.04-2695fje

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