Article
Lack of association of birth size with polymorphisms of two imprinted genes, IGF2R and GRB10.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Sept 2004
Kukuvitis A, Georgiou I, Syrrou M, Andronikou S, Dickerman Z, Islam A, McCann J, Polychronakos C
Abstract excerpt
Little is known about the determinants of birth size variability among individuals. Maternal and nutritional factors have been studied, but familial clustering suggests genetic factors as well. As a first step in testing this hypothesis, we examined common sequence variants in IGF2R and GRB10, two genes involved in the regulation of growth and subject to parental imprinting. The IGF2R gene was scanned with five...
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