Article
The effect of mutation on Rhodococcus equi virulence plasmid gene expression and mouse virulence.
Veterinary microbiology - 15 Nov 2004
Ren Jun, Prescott John F
Abstract excerpt
An 81 kb virulence plasmid containing a pathogenicity island (PI) plays a crucial role in the pathogenesis of Rhodococcus equi pneumonia in foals but its specific function in virulence and regulation of plasmid-encoded virulence genes is unclear. Using a LacZ selection marker developed for R. equi in this study, in combination with an apramycin resistance gene, an efficient two-stage homologous recombination...
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