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Deletion of <i>vapA</i> encoding Virulence Associated Protein A attenuates the intracellular actinomycete <i>Rhodococcus equi</i>

20 Aug 2003

Abstract excerpt

Virulent strains of the facultative intracellular bacterium Rhodococcus equi isolated from young horses (foals) with R. equi pneumonia, carry an 80-90 kb virulence plasmid and express a highly immunogenic 15-17 kDa protein of unknown function called VapA (Virulence Associated Protein A). Recent sequencing of the virulence plasmid identified a putative pathogenicity island encoding a novel family of seven Vap...

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PMID: 14507368
DOI: 10.1046/j.1365-2958.2003.03689.x

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