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Article

Fibroblast growth factor-2 stimulates interleukin-6 secretion in human pancreatic periacinar myofibroblasts.

Pancreas - 1 Nov 2004

Andoh Akira, Bamba Shigeki, Fujino Sanae, Inatomi Osamu, Zhang Zhuobin, Kim Shokei, Takayanagi Atsushi, Shimizu Nobuyoshi, Fujiyama Yoshihide

Abstract excerpt

OBJECTIVES: Fibroblast growth factor-2 (FGF-2) plays an important role in the pathophysiology of acute and chronic pancreatitis. In the present study, to evaluate the proinflammatory nature of FGF-2, we investigated the effects of FGF-2 on IL-6 secretion in human pancreatic periacinar myofibroblasts. METHODS: IL-6 supernatant levels were determined by enzyme-linked immunosorbent assays (ELISA). IL-6 mRNA...

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PMID: 15502643
DOI: 10.1097/00006676-200411000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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