Article
Enabling large-scale pharmacogenetic studies by high-throughput mutation detection and genotyping technologies.
Clinical chemistry - 1 Feb 2001
Shi M M
Abstract excerpt
BACKGROUND: Pharmacogenetics is a scientific discipline that examines the genetic basis for individual variations in response to therapeutics. Pharmacogenetics promises to develop individualized medicines tailored to patients' genotypes. However, identifying and genotyping a vast number of genetic polymorphisms in large populations also pose a great challenge. APPROACH: This article reviews the recent technology...
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