Article
Detection and characterization of oncogene mutations in preneoplastic and early neoplastic lesions.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Minamoto Toshinari
Abstract excerpt
Although it has been more than 20 yr since its discovery, the ras family of genes has not yet lost its impact on basic and clinical oncology. These genes remain central to the field of molecular oncology as tools for investigating carcinogenesis and oncogenic signaling, as powerful biomarkers for the identification of those who have or are at high risk of developing cancer, and as oncogene targets for the design...
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