Article
Biosynthesis of biotin and lipoic acid.
Vitamins and hormones - 1 Jan 2001
Marquet A, Bui B T, Florentin D
Abstract excerpt
The genetics and mechanistic enzymology of biotin biosynthesis have been the subject of much investigation in the last decade, owing to the interest for biotin production by fermentation, on the one hand, and for the design of inhibitors with potential herbicidal properties, on the other hand. Four enzymes are involved in the synthesis of biotin from its two precursors, alanine and pimeloyl-CoA. They are now...
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