Article
Human epicardium-derived cells fuse with high efficiency with skeletal myotubes and differentiate toward the skeletal muscle phenotype: a comparison study with stromal and endothelial cells.
Molecular biology of the cell - 1 Mar 2011
Gentile Antonietta, Toietta Gabriele, Pazzano Vincenzo, Tsiopoulos Vasileios D, Giglio Ada Francesca, Crea Filippo, Pompilio Giulio, Capogrossi Maurizio C, Di Rocco Giuliana
Abstract excerpt
Recent studies have underscored a role for the epicardium as a source of multipotent cells. Here, we investigate the myogenic potential of adult human epicardium-derived cells (EPDCs) and analyze their ability to undergo skeletal myogenesis when cultured with differentiating primary myoblasts. Results are compared to those obtained with mesenchymal stromal cells (MSCs) and with endothelial cells, another...
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