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Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type β-lactamase

15 Oct 2004

Abstract excerpt

OBJECTIVE: In the past decade, a new problem in Klebsiella pneumoniae strains has emerged: plasmid-mediated AmpC enzymes. This study was conducted to investigate the activity of cefepime against clinical isolates by determining the activities of cefepime and three other parenteral beta-lactam agents in standard and high inoculum MIC tests. METHODS: A total of 61 K. pneumoniae blood isolates, including 28 isolates...

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PMID: 15486080
DOI: 10.1093/jac/dkh462

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