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Article

Interaction of implantable defibrillator therapy with angiotensin-converting enzyme deletion/insertion polymorphism.

Journal of cardiovascular electrophysiology - 1 Oct 2004

Bedi Maninder S, Postava Lisa A, Murali Srinivas, Macgowan Guy A, Mathier Michael, McNamara Dennis M, London Barry

Abstract excerpt

INTRODUCTION: The angiotensin-converting enzyme deletion allele (ACE D) decreases survival in patients with advanced heart failure. Whether the adverse impact on survival reflects an increased risk of pump failure or arrhythmic sudden death remains uncertain. If the ACE D genotype increases the risk of sudden death, implantable cardioverter defibrillator (ICD) therapy should diminish its negative impact. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Peptidyl-Dipeptidase A

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Source

Identifiers

PMID: 15485441
DOI: 10.1046/j.1540-8167.2004.03609.x

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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