Characterization of hepatitis B virus mutations in untreated patients co-infected with HIV and HBV based on complete genome sequencing.

Abstract excerpt

Co-infection of HBV with HIV results in an accelerated course of HBV-associated chronic liver disease. Several studies have shown that viral mutations are related to disease progression in mono-infection with HBV. However, it is unclear whether HBV mutation patterns might differ between co-infected and mono-infected patients. To compare the frequencies and mutation patterns in the HBV genome between co-infection...

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