Article
Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote.
BMC genomics - 12 Oct 2004
Ward Pauline, Equinet Leila, Packer Jeremy, Doerig Christian
Abstract excerpt
BACKGROUND: Malaria, caused by the parasitic protist Plasmodium falciparum, represents a major public health problem in the developing world. The P. falciparum genome has been sequenced, which provides new opportunities for the identification of novel drug targets. Eukaryotic protein kinases (ePKs) form a large family of enzymes with crucial roles in most cellular processes; hence malarial ePKS represent...
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