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Article

Deposition of transthyretin amyloid is not accelerated by the same amyloid in vivo.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Jun 2004

Wei Lan, Kawano Hiroo, Fu Xiaoying, Cui Dan, Ito Sadahiro, Yamamura Ken-ichi, Ishihara Tokuhiro, Tokuda Takahiko, Higuchi Keiichi, Maeda Shuichiro

Abstract excerpt

Acceleration of amyloid deposition by administration of amyloid fibrils and transmissibility of disease have been reported in several types of amyloidoses. Families with a variant transthyretin (TTR V30M)-associated familial amyloidotic polyneuropathy (FAP) exhibit genetic anticipation, with TTR V30M-amyloid depositing at an earlier age in successive generations. The molecular bases of anticipation in FAP have...

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Identifiers

PMID: 15478467
DOI: 10.1080/13506120410001726344

Genes

TTR
FAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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