Article
Translational control of the rat angiotensin type 1a receptor by alternative splicing.
Gene - 27 Oct 2004
Zhang Yinghua, Ji Hong, Fabucci Maria Elena, Falconetti Celine, Zheng Wei, Sandberg Kathryn
Abstract excerpt
The rat angiotensin type 1a receptor (AT1aR) is comprised of three exons. Two transcripts are possible due to alternative splicing of exon 2 (E1,3 and E1,2,3). Both transcripts code for identical AT1aR proteins since they differ only in the length of their 5' leader sequence (5'LS). We investigated the functional differences of these two transcripts in stably transfected Chinese hamster ovary (CHO) cells and also...
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