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Article

Genomic instability in multiple myeloma: Evidence for jumping segmental duplications of chromosome arm 1q

7 Oct 2004

Abstract excerpt

Multiple myeloma (MM) is a malignant plasma cell disorder characterized by complex karyotypes and chromosome 1 instability at the cytogenetic level. Chromosome 1 instability generally involves partial duplications, whole-arm translocations, or jumping translocations of 1q, identified by G-banding. To characterize this instability further, we performed spectral karyotyping and fluorescence in situ hybridization...

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Share to Chromosomal and Genetic Variations
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PMID: 15472896
DOI: 10.1002/gcc.20109

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