Article
Immunogenetic susceptibility of atherosclerotic stroke: implications on current and future treatment of vascular inflammation.
Stroke - 1 Nov 2004
DeGraba Thomas J
Abstract excerpt
The understanding of the pathophysiology governing atherosclerosis supports a prominent role for inflammation pathways in plaque initiation and progression that result in stroke and myocardial infarction. Elevated levels of inflammatory markers in the blood, such as C-reactive protein and CD40 ligand/CD40, in concert with increased expression of adhesion molecules, chemokines, cytokines, matrix metalloproteinases...
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