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Article

Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues.

The International journal of developmental biology - 1 Sept 2004

Liu Fei, Woitge Henning W, Braut Alen, Kronenberg Mark S, Lichtler Alexander C, Mina Mina, Kream Barbara E

Abstract excerpt

The Cre/loxP recombination system can be used to circumvent many of the limitations of generalized gene ablation in mice. Here we present the development and characterization of transgenic mice in which Cre recombinase has been targeted to cells of the osteoblast lineage with 2.3 kb (Col 2.3-Cre) and 3.6 kb (Col 3.6-Cre) fragments of the rat Col1a1 promoter. Cre mRNA was detected in calvaria and long bone of...

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PMID: 15470637
DOI: 10.1387/ijdb.041816fl

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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