Article
Identification of <i>Cryptococcus neoformans</i> Temperature-Regulated Genes with a Genomic-DNA Microarray
1 Oct 2004
Abstract excerpt
The ability to survive and proliferate at 37 degrees C is an essential virulence attribute of pathogenic microorganisms. A partial-genome microarray was used to profile gene expression in the human-pathogenic fungus Cryptococcus neoformans during growth at 37 degrees C. Genes with orthologs involved in stress responses were induced during growth at 37 degrees C, suggesting that a conserved transcriptional program...
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