Article
E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma.
Oncogene - 11 Nov 2004
Saito Tsuyoshi, Oda Yoshinao, Kawaguchi Ken-ichi, Sugimachi Keishi, Yamamoto Hidetaka, Tateishi Naomi, Tanaka Kazuhiro, Matsuda Shuichi, Iwamoto Yukihide, Ladanyi Marc, Tsuneyoshi Masazumi
Abstract excerpt
We have recently reported frequent E-cadherin gene mutations in synovial sarcoma (SS), suggesting mutational inactivation of E-cadherin as a potential mechanism of spindle cell morphology in SS, a spindle cell sarcoma that shows areas of glandular epithelial differentiaton in some cases (biphasic...
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