Article
PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma.
Oncology reports - 1 May 2004
Saito Tsuyoshi, Oda Yoshinao, Kawaguchi Ken-Ichi, Takahira Tomonari, Yamamoto Hidetaka, Tanaka Kazuhiro, Matsuda Shuichi, Sakamoto Akio, Iwamoto Yukihide, Tsuneyoshi Masazumi
Abstract excerpt
Synovial sarcomas (SS) consistently show a characteristic chromosomal translocation, t(X;18)(p11;q11), which usually leads to the formation of 2 chimeric fusion transcripts, SYT-SSX1 and -SSX2. A recent multi-institutional retrospective study revealed that the SYT-SSX fusion type emerged as the o...
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