Article
Characterization of apoptosis-related oxidoreductases from Neurospora crassa.
PloS one - 1 Jan 2012
Carneiro Patrícia, Duarte Margarida, Videira Arnaldo
Abstract excerpt
The genome from Neurospora crassa presented three open reading frames homologous to the genes coding for human AIF and AMID proteins, which are flavoproteins with oxidoreductase activities implicated in caspase-independent apoptosis. To investigate the role of these proteins, namely within the mitochondrial respiratory chain, we studied their cellular localization and characterized the respective null mutant...
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