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Article

Eag1 potassium channels as markers of cervical dysplasia

31 Aug 2011

Abstract excerpt

Human ether à-go-go 1 (Eag1) potassium channels are potential tumor markers and therapeutic targets for several types of malignancies, including cervical cancer. Estrogens and human papilloma virus oncogenes regulate Eag1 gene expression, suggesting that Eag1 may already be present in pre-malignant lesions. Therefore, Eag1 could be used as an early marker and/or a potential risk indicator for cervical cancer....

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PMID: 21887469
DOI: 10.3892/or.2011.1441

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