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Article

H2-Ea deficiency is a risk factor for bleomycin-induced lung fibrosis in mice.

Cancer research - 1 Oct 2004

Du Min, Irani Roxanna A, Stivers David N, Lee Sang-Joon, Travis Elizabeth L

Abstract excerpt

Pulmonary fibrosis is a significant complication in cancer patients when treated by radiation, e.g., thoracic malignant diseases, or chemotherapeutic agents. Bleomycin is one of the primary drugs used to treat testicular cancer, but the incidence of significant pulmonary fibrosis limits the dose. It is known that susceptibility to bleomycin-induced pulmonary fibrosis is a heritable trait controlled by multiple...

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Identifiers

PMID: 15466168
DOI: 10.1158/0008-5472.CAN-04-1678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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