Article
Mitochondrial DNA heteroplasmy among hairs from single individuals.
Journal of forensic sciences - 1 Sept 2004
Sekiguchi Kazumasa, Sato Hajime, Kasai Kentaro
Abstract excerpt
A denaturing gradient gel electrophoresis (DGGE) assay was used to detect mitochondrial DNA (mtDNA) sequence heteroplasmy in 160 hairs from each of three individuals. The HV1 and HV2 heteroplasmic positions were then identified by sequencing. In several hairs, the heteroplasmic position was not evident by sequencing and dHPLC separation of the homoduplex/heteroduplex species was carried out with subsequent...
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