Article
Differences in tissue distribution of HV2 length heteroplasmy in mitochondrial DNA between mothers and children.
Forensic science international - 5 Mar 2008
Asari Masaru, Azumi Jun-Ichi, Shimizu Keiko, Shiono Hiroshi
Abstract excerpt
Sequence analysis of HV2 in mitochondrial DNA has been performed as a tool for forensic identification, in addition to that of HV1. HV2 contains length heteroplasmy, which shows high variability within an individual or in maternal relatives. In this study, we used cloning analysis and PCR direct sequencing to compare, between mothers and their children, HV2 length heteroplasmic profiles in different tissues. For...
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