Article
Differential distribution of human mitochondrial DNA in somatic tissues and hairs.
Annals of human genetics - 1 Jan 2006
Lee Hwan Young, Chung Ukhee, Park Myung Jin, Yoo Ji-Eun, Han Gil-Ro, Shin Kyoung-Jin
Abstract excerpt
To investigate mitochondrial DNA (mtDNA) distribution within tissues during life, we observed length heteroplasmy in a polycytosine tract of the mitochondrial HV2 region by size-based separation of PCR products, using a mutagenic primer which was designed to avoid stutter production. Blood, brain, heart, liver, skeletal muscle and hair shaft samples were collected during autopsies of 25 individuals. Here, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
